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Index > Protein center > ACTB(Gene name) > Bovine
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  • ACTB (Gene name),
  • Actin, cytoplasmic 1 (Protein name ),  ACTB_BOVIN from NCBI database.
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  • Gene name:
    ACTB;
    Protein name:
    Actin, cytoplasmic 1;
    Alternative:
    Beta-actin;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2.
    Function:
    Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
    Subcellular Location:
    Cytoplasm cytoskeleton Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
    Protein Attributes:
    Sequence length:
    375
    Sequence:
    50:
    MDDDIAALVV | DNGSGMCKAG | FAGDDAPRAV | FPSIVGRPRH | QGVMVGMGQK | 
    100:
    DSYVGDEAQS | KRGILTLKYP | IEHGIVTNWD | DMEKIWHHTF | YNELRVAPEE | 
    150:
    HPVLLTEAPL | NPKANREKMT | QIMFETFNTP | AMYVAIQAVL | SLYASGRTTG | 
    200:
    IVMDSGDGVT | HTVPIYEGYA | LPHAILRLDL | AGRDLTDYLM | KILTERGYSF | 
    250:
    TTTAEREIVR | DIKEKLCYVA | LDFEQEMATA | ASSSSLEKSY | ELPDGQVITI | 
    300:
    GNERFRCPEA | LFQPSFLGME | SCGIHETTFN | SIMKCDVDIR | KDLYANTVLS | 
    350:
    GGTTMYPGIA | DRMQKEITAL | APSTMKIKII | APPERKYSVW | IGGSILASLS | 
    375:
    TFQQMWISKQ | EYDESGPSIV | HRKCF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
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    ELISA Kit for Bovine Actin, cytoplasmic 1
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    ELISA Kit for Bovine Actin, cytoplasmic 1
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    ELISA Kit for Bovine Actin, cytoplasmic 1
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    ELISA Kit for Bovine Actin, cytoplasmic 1
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    ELISA Kit for Bovine Actin, cytoplasmic 1
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    CLIA Kit for Bovine Actin, cytoplasmic 1
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    CLIA Kit for Bovine Actin, cytoplasmic 1
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    CLIA Kit for Bovine Actin, cytoplasmic 1
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    CLIA Kit for Bovine Actin, cytoplasmic 1
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    CLIA Kit for Bovine Actin, cytoplasmic 1
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    CLIA Kit for Bovine Actin, cytoplasmic 1
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    CLIA Kit for Bovine Actin, cytoplasmic 1
    MSDS:
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    CLIA Kit for Bovine Actin, cytoplasmic 1
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    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
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    P8725Rb-h
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    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
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    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
    Polyclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Monoclonal Antibody for Bovine Actin, cytoplasmic 1
    Protein for Bovine Actin, cytoplasmic 1
    Protein for Bovine Actin, cytoplasmic 1
    Protein for Bovine Actin, cytoplasmic 1
    Cat.:
    R8725h
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Bovine Actin, cytoplasmic 1
    Protein for Bovine Actin, cytoplasmic 1
    Protein for Bovine Actin, cytoplasmic 1
    Protein for Bovine Actin, cytoplasmic 1
    Protein for Bovine Actin, cytoplasmic 1

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    References
    1. 1.
      "Bovine mammary gene expression profiling using a cDNA microarray enhanced for mammary-specific transcripts."
      Suchyta S.P. , Sipkovsky S. , Halgren R.G. , Kruska R. , Elftman M. , Weber-Nielsen M. , Vandehaar M.J. , Xiao L. , Tempelman R.J. , Coussens P.M.
      Physiol. Genomics16:8-18(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Mammary gland.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Crossbred X Angus.
      strain: Hereford.
      tissue: Ileum.
      tissue: Thymus.
    4. 4.
      "Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin."
      Vandekerckhove J. , Weber K.
      Eur. J. Biochem.90:451-462(1978) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-375
      tissue: Brain.
    5. 5.
      "Regulation of protein synthesis in mitogen-activated bovine lymphocytes. Analysis of actin-specific and total mRNA accumulation and utilization."
      Degen J.L. , Neubauer M.G. , Friezner Degen S.J. , Seyfried C.E. , Morris D.R.
      J. Biol. Chem.258:12153-12162(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 77-228 AND 345-375
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.55 ANGSTROMS) OF COMPLEX WITH PROFILIN
    7. 7.
      "The structure of an open state of beta-actin at 2.65-A resolution."
      Chik J.K. , Lindberg U. , Schutt C.E.
      J. Mol. Biol.263:607-623(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF COMPLEX WITH PROFILIN
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